Doctors Best Vitamin D3 5000IU, 360 Softgels from Doctors Best

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Vitamin D from dietary intake or sun exposure requires two activation steps in the body. The first activation occurs in the liver, while the second activation occurs in the kidneys, allowing for regulation of calcium metabolism. Vitamin D receptors are present throughout the body, in tissue such as the skin, cartilage, heart, prostate, bones and intestines so the second activation step also takes place in local tissues. Vitamin D plays a role in most organs and systems of the body. It is hormone-like, known to interact with over 200 different genes, and plays a crucial regulatory role as a metabolic activator for a multitude of metabolic processes. It acts as a "molecular switch" by influencing the expression of multiple genes. Therefore activated vitamin D not only influences bone health, but is involved in supporting the function of the immune system, cardiovascular system, respiratory system and the musculoskeletal system.